8. The Adjuvanted Recombinant Zoster Vaccine (RZV) Confers Long-term Protection Against Herpes Zoster: Interim Results of an Extension Study (ZOSTER-049) of Two Clinical Trials (ZOE-50 and ZOE-70)
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چکیده
منابع مشابه
Vaccine against herpes zoster
The herpes zoster vaccine is made using high doses of live attenuated varicella/zoster virus. The vaccine is well tolerated and has few adverse effects: the most common one is pain at the injection site. Complications can occur mainly in persons who had prior zoster keratitis or uveitis. The vaccine can prevent this disease with low mortality but high morbidity.
متن کاملHerpes zoster caused by vaccine-strain varicella zoster virus in an immunocompetent recipient of zoster vaccine.
We report the first laboratory-documented case of herpes zoster caused by the attenuated varicella zoster virus (VZV) contained in Zostavax in a 68-year-old immunocompetent adult with strong evidence of prior wild-type VZV infection. The complete genome sequence of the isolate revealed that the strain carried 15 of 42 (36%) recognized varicella vaccine-associated single-nucleotide polymorphisms...
متن کاملEfficacy of the Herpes Zoster Subunit Vaccine in Adults 70 Years of Age or Older.
BACKGROUND A trial involving adults 50 years of age or older (ZOE-50) showed that the herpes zoster subunit vaccine (HZ/su) containing recombinant varicella-zoster virus glycoprotein E and the AS01B adjuvant system was associated with a risk of herpes zoster that was 97.2% lower than that associated with placebo. A second trial was performed concurrently at the same sites and examined the safet...
متن کاملAdjuvanted Herpes Zoster Subunit Vaccine in Older Adults.
n engl j med 373;16 nejm.org october 15, 2015 1575 Observations from each trajectory are also interesting (Table 1). An FEV1 that is normal at cohort inception without COPD at the final examination (trajectory 1) seems reasonable. An FEV1 that is normal or low at cohort inception with concomitant COPD at the final examination (trajectories 3 and 4) does also, especially considering the authors’...
متن کاملHerpes Zoster and Recurrent Herpes Zoster
BACKGROUND The incidence of recurrent herpes zoster (HZ) and the relationship between initial and recurrent HZ are not clear. METHODS The Miyazaki Dermatologist Society has surveyed ~5000 patients with HZ annually since 1997. A questionnaire regarding HZ and its recurrence was completed by the dermatologists. RESULTS A total of 34 877 patients with HZ were registered at 43 clinics between J...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2020
ISSN: 2328-8957
DOI: 10.1093/ofid/ofaa417.007